Endocrinology

Six months before presentation, Buster was presented to his primary veterinarian for polyuria, polydipsia, and weight loss. Physical examination and complete blood count (CBC) were unremarkable, while the serum biochemical profile demonstrated: mildly increased alkaline phosphatase (ALP)…

Aside from a histologic confirmation of insulinoma, no currently available diagnostic test provides a definitive diagnosis of insulinoma. Existing techniques may help increase suspicion for an insulin-secreting tumor but, with most diagnostic testing, it is imperative to interpret all results in the context of the coexisting clinical signs.

The owner reported that Lucky vomited in the car a week earlier when coming home from the groomer. Over the past week, Lucky’s appetite diminished but she seemed thirstier. Lucky had become progressively more lethargic and anorectic over the past 2 days….

Glycemic control in diabetic dogs and cats may be jeopardized by hospitalization for treatment of diabetic or nondiabetic disorders or routine health care interventions, such as minor surgical procedures or dental prophylaxis. Thus, a major challenge for veterinarians caring for established diabetics in the hospital is to provide needed care while avoiding significant disruption of glucose control. This article provides useful strategies and techniques for in-hospital glucose management in established stable diabetics.

Canine pituitary dependent hyperadrenocorticism (PDH), also known as Cushing’s disease, is a common endocrine disorder in older dogs. This disorder is caused by a pituitary adenoma (PA) that secretes inappropriate amounts of adrenocorticotropic hormone (ACTH)…

David Bruyette, DVM, Diplomate ACVIM VCA West Los Angeles Animal Hospital, Los Angeles, California, and Veterinary Diagnostic Investigation and Consultation, Woodland Hills, California Canine pituitary dependent hyperadrenocorticism (PDH), also known as Cushing’s disease, is a common endocrine disorder in older dogs. This disorder is caused by a pituitary adenoma (PA) that secretes inappropriate amounts of …

Canine pituitary dependent hyperadrenocorticism (PDH), also known as Cushing’s disease, is a common endocrine disorder in older dogs. This disorder is caused by a pituitary adenoma (PA) that secretes inappropriate amounts of adrenocorticotropic hormone (ACTH)…

Ann Della Maggiore, DVM, Diplomate ACVIM University of California—Davis Sugar, a 12-year-old spayed female Maine Coon cat, presented for poorly controlled diabetes and diabetic neuropathy. HISTORY Sugar was diagnosed with diabetes mellitus 2 years prior to presentation. Initially, her diabetes was moderately controlled on 5 to 6 units of recombinant human protamine zinc insulin (PZI) …

Maya Lottati DVM, PhD, and David Bruyette, DVM, Diplomate ACVIM (Internal Medicine) Addison’s disease has an overall low disease prevalence, and when combined with vague clinical signs and nonspecific clinicopathologic abnormalities, diagnosis is challenging. The authors identify the function of the adrenal cortex, forms of the disease, diagnostics, acute therapy, and long-term maintenance. Canine hypoadrenocorticism, …