Oclacitinib: Treating Pruritus and Beyond
For years, glucocorticoids and cyclosporine have been used for the symptomatic management of atopic dermatitis, including the associated pruritus. In the past 5 years, however, oclacitinib (Apoquel; zoetisus.com), a Janus kinase (JAK) inhibitor, has become another important drug in the management of allergic pruritus.
Grapiprant for Control of Osteoarthritis Pain in Dogs
For centuries, nonsteroidal anti-inflammatory drugs (NSAIDs) have been used for pain control. However, their use has been associated with potentially life-threatening adverse drug events. Grapiprant is a novel drug for treatment of osteoarthritic pain in dogs. Approved in 2016, it is a non-cyclooxygenase (COX)-inhibiting NSAID.
The Use of Capromorelin for the Clinical Problem of Inappetence
Inappetence is a common clinical sign that has an important influence on perceived quality of life and case management in dogs and cats. Capromorelin has the potential to positively affect the clinical management of inappetence and weight loss/cachexia in dogs.
Alfaxalone: An Old Drug in a New Formulation
Alfaxalone has been used to induce general anesthesia for many years, but only recently has a new formulation with preservatives become available in the United States. This formulation has a shelf life of 28 days after first use. It is approved for IV administration to induce and maintain general anesthesia in dogs and cats; however, it is also used via the IM route for induction and sedation (off label).
Mirtazapine: Addressing Appetite in Cats
A review of the studies of oral mirtazapine—which stimulates appetite—and current recommendations for cats, including normal cats, geriatric cats, and cats with kidney or liver disease.
Pimobendan and Heart Disease
Pimobendan is a benzimidazole-pyridazinone derivative, labeled for use in dogs to manage congestive heart failure (CHF) resulting from dilated cardiomyopathy (DCM) or degenerative mitral valve disease (DMVD) in the United States. On the basis of its positive inotropic effects combined with arteriovenous dilation, it is classified as an inodilator.1 In this article, we provide relevant …
Hypothermia in the Operating Room
Keeping any anesthetized animal from hypothermia before, during, and after surgery is challenging. Here’s how to keep the patient warm.
Ferret Distemper: What You Need to Know
Leonie Kondert, DVM Joerg Mayer, DVM, MS, DABVP, DACZM University of Georgia Distemper is an acute viral infectious disease with reported mortality rates in ferrets of 100%.1–5 Prevalence depends on the area, recent outbreaks have been documented in multiple countries.1,4 Since the invention of a vaccine against canine distemper virus (CDV) in the 1960s, the …
Leptospirosis is a bacterial disease that is of importance in human and veterinary medicine due to its zoonotic potential. With early and aggressive treatment that includes attentive monitoring, prognosis for recovery is excellent.