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Pimobendan and Heart Disease

Pimobendan is a benzimidazole-pyridazinone derivative, labeled for use in dogs to manage congestive heart failure (CHF) resulting from dilated cardiomyopathy (DCM) or degenerative mitral valve disease (DMVD) in the United States. On the basis of its positive inotropic effects combined with arteriovenous dilation, it is classified as an inodilator.1 In this article, we provide relevant …

Ferret Distemper: What You Need to Know

Leonie Kondert, DVM Joerg Mayer, DVM, MS, DABVP, DACZM University of Georgia Distemper is an acute viral infectious disease with reported mortality rates in ferrets of 100%.1–5 Prevalence depends on the area, recent outbreaks have been documented in multiple countries.1,4 Since the invention of a vaccine against canine distemper virus (CDV) in the 1960s, the …

Leptospirosis

Leptospirosis is a bacterial disease that is of importance in human and veterinary medicine due to its zoonotic potential. With early and aggressive treatment that includes attentive monitoring, prognosis for recovery is excellent.

Use of Antibiotics for Treating UTIs in Dogs and Cats

Understanding drug pharmacokinetics and pharmacodynamics is essential when determining the most effective antibiotic therapy for UTIs in dogs and cats.

Most UTIs in dogs and cats are successfully treated with commonly used drugs, dosages, and administration intervals. However, infections can be challenging to effectively treat when they involve the kidneys (pyelonephritis) and prostate (prostatitis)…

Oral Cyclosporine Use in Dogs


 Todd Archer, DVM, MS, Diplomate ACVIM, and Andrew Mackin, BSc, BVMS, Diplomate ACVIM, Mississippi State University Originally derived from a soil fungus, cyclosporine is a powerful immunosuppressive drug that was initially used in humans to prevent rejection of transplanted organs.1-3 In 2003, oral cyclosporine capsules (Atopica, novartis.com) received Food and Drug Administration (FDA) approval …

Methimazole: Management of Feline Hyperthyroidism

David Bruyette, DVM, Diplomate ACVIM (Internal Medicine) VCA West Los Angeles Animal Hospital & Veterinary Diagnostic Investigation and Consultation Methimazole (oral and transdermal) is a safe and effective medication for the treatment of feline hyperthyroidism. Dr. Bruyette discusses drug administration and monitoring, plus 10 key points of owner education. Methimazole is commonly used for the …

Management of Chronic Pain in Cats

Dinah G. Jordan, BSPh, RPh, Pharm D, FSVHP, Diplomate ICVP, and Joel D. Ray, DVM, MS Chronic pain in cats is commonly associated with malignancy, chronic inflammation, orthopedic disorders, chronic soft tissue injury, and nervous tissue injury.1 It is often difficult to recognize because the signs may be subtle, such as:2 Hiding/withdrawing from humans or other …

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