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Alfaxalone: An Old Drug in a New Formulation

Alfaxalone has been used to induce general anesthesia for many years, but only recently has a new formulation with preservatives become available in the United States. This formulation has a shelf life of 28 days after first use. It is approved for IV administration to induce and maintain general anesthesia in dogs and cats; however, it is also used via the IM route for induction and sedation (off label).

Clinical Insights

Pimobendan and Heart Disease

Pimobendan is a benzimidazole-pyridazinone derivative, labeled for use in dogs to manage congestive heart failure (CHF) resulting from dilated cardiomyopathy (DCM) or degenerative mitral valve disease (DMVD) in the United States. On the basis of its positive inotropic effects combined with arteriovenous dilation, it is classified as an inodilator.1 In this article, we provide relevant …

Focus On: Ferret Distemper—What You Need to Know

Leonie Kondert, DVM Joerg Mayer, DVM, MS, DABVP, DACZM University of Georgia Distemper is an acute viral infectious disease with reported mortality rates in ferrets of 100%.1–5 Prevalence depends on the area, recent outbreaks have been documented in multiple countries.1,4 Since the invention of a vaccine against canine distemper virus (CDV) in the 1960s, the …

Focus On: Leptospirosis

Leptospirosis is a bacterial disease that is of importance in human and veterinary medicine due to its zoonotic potential. With early and aggressive treatment that includes attentive monitoring, prognosis for recovery is excellent.

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Use of Antibiotics for the Urinary Tract

Most UTIs are successfully treated with commonly used drugs, dosages, and administration intervals. However, infections can be challenging to effectively treat when they involve the kidneys (pyelonephritis) and prostate (prostatitis)…

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