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Pharmacology

Oral Cyclosporine Use in Dogs

Originally derived from a soil fungus, cyclosporine is a powerful immunosuppressive drug that was initially used in humans to prevent rejection of transplanted organs.1-3 In 2003, oral cyclosporine capsules (Atopica, novartis.com) received Food and Drug Administration (FDA) approval for treatment of atopy in dogs. Extralabel use of cyclosporine includes: Treatment of a variety of inflammatory …

Methimazole: Management of Feline Hyperthyroidism

David Bruyette, DVM, Diplomate ACVIM (Internal Medicine) VCA West Los Angeles Animal Hospital & Veterinary Diagnostic Investigation and Consultation Methimazole (oral and transdermal) is a safe and effective medication for the treatment of feline hyperthyroidism. Dr. Bruyette discusses drug administration and monitoring, plus 10 key points of owner education. Methimazole is commonly used for the …

Management of Chronic Pain in Cats

Dinah G. Jordan, BSPh, RPh, Pharm D, FSVHP, Diplomate ICVP, and Joel D. Ray, DVM, MS Chronic pain in cats is commonly associated with malignancy, chronic inflammation, orthopedic disorders, chronic soft tissue injury, and nervous tissue injury.1 It is often difficult to recognize because the signs may be subtle, such as:2 Hiding/withdrawing from humans or other …

Fundamentals for Today’s Insulin Therapy

  Michael Schaer, DVM, Diplomate ACVIM & ACVECC & Thomas Schermerhorn, VMD, Diplomate ACVIM (Small Animal Internal Medicine) The veterinary profession has had to adjust the treatment of the diabetic patient due to changes in insulin production and availability. Most of the products used in dogs and cats are dictated by products used in humans. …

Ketamine: To Use or Not to Use for Pain Management

Ketamine is a useful adjunct to many surgical procedures as one of the most potent drugs available for NMDA-blockade.

  Ketamine has been in long and routine use as a dissociative anesthetic. More recently, new pharmacologic features of ketamine have been discovered that provide novel pain modification. Editor’s Note: This article was originally published in July 2011. Please use this content for reference or educational purposes, but note that it is not being actively …

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