Gastroenterology , Issues in Gastrointestinal Disorders

Diagnosing Acute Pancreatitis in Dogs

Stuart A. Walton BVSc, BScAgr, MANZCVS (SAIM), DACVIM

Dr. Walton is a clinical assistant professor in small animal internal medicine at the University of Florida. He earned his veterinary degree at the University of Queensland in Australia and has completed 2 internal medicine residencies; the first at Veterinary Specialist Services (Australia) and the second at Louisiana State University. His many interests include infectious and inflammatory diseases, immune-mediated disease, respiratory disease, and extracorporeal blood purification techniques.

Diagnosing Acute Pancreatitis in Dogs
BEYOND THE BASICS Due to the wide range of clinical signs and possible causes for pancreatitis, there are multiple tests and methods for determining the diagnosis of pancreatitis. Yulianna Asinovskaya/

The pancreas, a tubuloalveolar gland situated in the right cranial quadrant caudal to the stomach, is composed of two separate tissues, referred to as the exocrine and endocrine pancreata.1 The exocrine pancreas, which comprises about 98% of the pancreatic mass, secretes zymogens (inactive pancreatic enzymes) and active enzymes that enable the digestion of carbohydrates, proteins, and triglycerides.

Pancreatitis causes significant illness in dogs and is considered to be the most common disease of the exocrine pancreas, although the exact prevalence is unknown.1-11 A recent study evaluating dogs that had been necropsied found that 8% showed macroscopic evidence of pancreatitis and approximately 37% had microscopic lesions suggestive of either acute or chronic pancreatitis.12

Despite raised awareness of, increased knowledge about, and new diagnostic tests for pancreatitis, the mortality rate in dogs is high, ranging from 27% to 58%.2,5,8,10,13,14 These rates are possibly overestimated, as they are based on study populations from referral institutions. Referred animals often have systemic effects associated with severe, complicated pancreatitis that requires intensive treatment and hospitalization rather than mild, self-limiting disease.4,13

The diagnosis of acute pancreatitis can be difficult because clinical signs and results of diagnostic testing are often nonspecific. This article addresses the diagnostic approach to patients with signs suggestive of pancreatitis; treatment of pancreatitis will be addressed in the March/April issue.


The underlying pathophysiology of acute pancreatitis is incompletely understood, with current understanding extrapolated from human and experimental models.1-3,15 The pathogenesis is complex, involving multiple inflammatory pathways.15 Regardless of the inciting cause, it is accepted that acute pancreatitis is initiated through dysregulated, uncontrolled activation of pancreatic proteolytic enzymes within acinar cells and the overwhelming of safeguards within the acinar cells and the systemic circulation.1,3,4,15-18 Initially, this results in excessive activation of trypsin, which then results in further activation of all zymogens within pancreatic tissue.3,15,18,19

If more than 10% of acinar trypsin is activated and plasma protease inhibitors are depleted, pancreatic safeguards (i.e., pancreatic secretory trypsin inhibitor) are overwhelmed.3,15,18,19 Release of the pancreatic enzymes into the pancreatic tissue results in neutrophilic inflammation of the pancreatic and peripancreatic fat. A complex and interdependent “cytokine storm” ensues, leading to production of reactive oxygen species, nitric oxide, and cytokines, as well as activation of other pathways (complement, kinin-kallikrein, and renin-angiotensin systems), which further perpetuates the local inflammatory reaction.3 The end result is digestive enzyme damage not only to the acinar cell, but to the vascular endothelium, producing microcirculatory changes, vasoconstriction, capillary stasis, progressive ischemia, and edema of the pancreas.3,18 Generated inflammatory free radicals and inflammatory cytokines may be released into the circulation, which may lead to organ failure (e.g., acute respiratory distress syndrome and acute kidney injury).20,21


Acute pancreatitis is reversible unless the initial trigger persists or there is chronic recurrent inflammation.3,5,16,19 In veterinary medicine, the pathologic description depends on histologic descriptions, with different forms of pancreatitis (e.g., acute necrotizing, acute, chronic) overlapping in clinical presentation.3,16

No single clinical sign or combination of clinical signs is pathognomonic for pancreatitis.2,10,16 Clinical signs are nonspecific and rely on the degree and severity of local pancreatic inflammation as well as the existence of concurrent systemic complications (Box 1).2,3,19

BOX 1 Common Clinical Findings in Dogs With Acute Pancreatitis6,9,22–25
  • Decreased appetite/anorexia
  • Vomiting
  • Abdominal pain
  • Weakness/lethargy
  • Diarrhea
  • Dehydration

Dogs with subclinical or mild disease can display nonspecific signs such as intermittent anorexia and weakness with no gastrointestinal signs. These may be self-limiting or may require supportive medical therapy.5,8 Dogs presenting with severe disease may present with signs referable to cardiovascular shock, disseminated intravascular coagulation, or multiorgan failure and die within hours of the development of clinical signs.16


Most cases of acute pancreatitis are considered to be idiopathic, with no identified inciting cause.1,16 Dogs of any age can be affected; most dogs are middle-aged or older (>5 years).6,14,16,26 Several epidemiologic factors and pathologic conditions have been identified as potential risk factors (Box 2). Obese or overweight dogs older than 7 years are at a greater risk.3,6,14,27 Terriers (e.g., miniature schnauzers, Yorkshire terriers) and nonsporting breeds (e.g., miniature poodle) are at an increased risk, although lifestyle (i.e., diet and exercise) may be factors that contribute to the development of pancreatitis in these breeds.14 Neutered status has been associated with the development of acute pancreatitis;27 however, in the author’s opinion, this may not be a true association, as it cannot be distinguished from the effects of diet, lifestyle, and exercise. Cause-and-effect relationships have not been established for most published risk factors, with the veterinary literature consisting of single case reports and relatively small retrospective studies. The presence of a factor(s) along with compatible clinical signs should raise suspicion for pancreatitis.3,16

BOX 2 Risk Factors Associated With Acute Pancreatitis1,3,6,16,27

Epidemiologic factors

  • Breed (terriers, schnauzers, poodles, Cavalier King Charles spaniels)
  • Age
  • Dietary factors (low-protein/high-fat diets, ingestion of garbage and unusual food)
  • Obesity
  • Neutered/spayed

Pathologic conditions

  • Previous surgery (e.g., adrenalectomy, neuter, spay)
  • Hyperlipidemia
  • Endocrine disease (diabetes mellitus, hyperadrenocorticism, hypothyroidism)
  • Hypercalcemia
  • Adverse drug reactions (azathioprine, L-asparaginase, sulfonamides, zinc, clomipramine, hydrochlorothiazide, potassium bromide with phenobarbital)
  • Duct obstruction (i.e., ductal hypertension)
  • Duodenal/biliary reflux
  • Ischemia
  • Infectious (e.g., babesiosis, leishmaniasis)
  • Toxins (organophosphates)

Ingestion of unusual food items or garbage is linked to the development of pancreatitis (i.e., inappropriate food rather than the fat/protein content of food).3,27

Certain breeds likely have a genetic predisposition.1 Genetic studies of acute pancreatitis have focused on SPINK1 gene variations in miniature schnauzers.28,29 The SPINK1 gene codes for the pancreatic secretory trypsin inhibitor, which acts as a defense mechanism against premature activation of trypsinogen. Recently, the significance of previous findings has been called into question, with one gene variant being commonly identified in schnauzers both with and without a history of pancreatitis. Furthermore, a relationship between the SPINK1 gene variant and clinically detectable pancreatitis could not be confirmed.30


Diagnosis and the diagnostic approach to acute pancreatitis remain challenging due to the variable severity and inconsistent presenting clinical signs associated with the disease. In dogs presenting with acute gastrointestinal distress and abdominal pain, surgical disease requiring intervention must be initially ruled out (Figure 1). At the author’s institution, acute pancreatitis is considered a diagnostic differential in animals presenting with anorexia, vomiting, dehydration, and abdominal pain.

Hematology, Serum Biochemistry, and Urinalysis

Results of a complete blood count (CBC), serum biochemistry panel, and urinalysis convey general information about the patient and are useful in the diagnosis or exclusion of other diseases.16 However, these results are often nonspecific and highly variable and may be within normal limits in mild cases.16,18 Abnormalities, when present, are the result of hypovolemia and inflammation. In brief, changes include leukocytosis, thrombocytopenia, azotemia, and increased liver enzymes. Variable electrolyte abnormalities have been identified. In some cases, coagulation abnormalities may be present (i.e., prolonged activated clotting time, prothrombin time, or partial thromboplastin time), which are invariably associated with spontaneous bleeding.16

Diagnostic Imaging

Abdominal Radiography

Abdominal radiographs are insensitive for detecting abnormalities associated with pancreatitis.3,4,16,17 When present, radiographic findings are nonspecific and may include increased soft tissue opacity, decreased serosal detail in the right cranial abdomen, widened pyloric duodenal angle, displacement of the stomach and/or duodenum from their normal position, gaseous dilation of bowel loops, and abdominal effusions (Figure 2).3,6,31 In dogs presenting with acute gastrointestinal distress and abdominal pain, plain abdominal radiographs are cost-effective, logical, and practical when surgical disease is a possibility (Figure 1).

Abdominal Ultrasonography

Ultrasonography is the imaging method of choice and has become a readily available and commonly used imaging modality in general practice.3,16 Few studies have evaluated the diagnostic utility of abdominal ultrasonography for the diagnosis of pancreatitis.16 Based on previous reports, the sensitivity of abdominal ultrasonography is approximately 68% in dogs with severe acute pancreatitis.3,4,6,16,32 With the evolution and advancement in equipment quality and ultrasonographer experience, sensitivity has most likely increased; however, further studies are needed to assess this. The specificity of ultrasonography has not been evaluated because histology would be required to establish the diagnosis.3,16

Ultrasonography is better at detecting severe acute necrotizing pancreatitis than mild or subclinical pancreatitis. Ultrasonographic findings suggestive of pancreatitis include hypoechoic areas within the pancreas (indicating necrosis or fluid accumulations); hyperechoic peripancreatic mesentery (due to necrosis of peripancreatic fat); an enlarged, irregular pancreas; dilation of the pancreatic or biliary duct; and abdominal effusion (Figure 3).6,33

Contrast-enhanced ultrasonography has been investigated as a technique for improving the accuracy of diagnosing pancreatitis in a small number of dogs.4,34 The technique investigates tissue perfusion as well as lesional vascular patterns.4 Initial results from several studies identified decreased peak pancreatic perfusion and prolonged retention of contrast in the pancreas, most likely secondary to inflammation.4,34 Additional studies are warranted to determine whether this modality is superior to traditional abdominal ultrasonography.

Computed Tomography Angiography

Three-phase computed tomography angiography (CTA) has been evaluated in dogs with acute pancreatitis as a diagnostic and prognostication tool.12,35 Multiple changes have been demonstrated in the appearance of the pancreas, peripancreatic tissues, and adjacent vessels.12,35,36 In a recent study, dogs with more heterogeneous contrast enhancement spent a significantly longer duration in hospital (>5 days), had an increased number of relapses, and were significantly more likely to have portal vein thrombosis.12 Heterogenous contrast enhancement was correlated to increased Spec cPL (IDEXX Reference Laboratories; when compared with homogeneous pancreatic contrast enhancement.12 Initial findings indicate that CTA is an additional, superior diagnostic modality in evaluating dogs with suspect acute pancreatitis; however, further studies are warranted.

Serum Assays

Based on their increased activity in experimentally induced pancreatitis, serum amylase and lipase were previously used to assess for clinical pancreatitis.3,9,16 However, due to their poor sensitivities and specificities, they are no longer used to assess for spontaneous pancreatitis.9,16,37-39

Canine pancreatic lipase originates only from pancreatic acinar cells.9,40 During active pancreatic disease, cPL leaks into the serum, leading to an increase in measurable cPL levels.9,23,38,39 Initially, a radioimmunoassay measuring cPL immunoreactivity was developed and validated.23,38,41 This assay has now been replaced by a quantitative (Spec cPL) and a semi-quantitative (SNAP cPL, colorimetric rapid point-of-care enzyme-linked immunosorbent assay (ELISA).9,23,38,39,42 Both tests are now routinely used in veterinary medicine, with the SNAP cPL test being used to rapidly rule out pancreatitis. It is recommended that positive SNAP cPL results be followed by laboratory assessment using the quantitative immunoassay (Spec cPL or equivalent).9 Spec cPL results ≤200 µg/L are consistent with an absence of pancreatic inflammation, while results ≥400 µg/L are consistent with a diagnosis of pancreatitis. Results of 200 to 399 µg/L are considered to be equivocal, and further testing using quantitative analysis is recommended in 2 to 3 weeks.9,16,23,39,42

Newer diagnostic assays—the VetScan cPL rapid point-of-care test (quantitative assay; Abaxis, and the Precision PSL (Antech;, a nonimmunologic colorimetric lipase diagnostic assay using 1,2-o-dilauryl-rac-glycero-3-glutaric acid (6′-methyl-resorufin) ester (DGGR)—have now been validated for use in dogs.7,9,43 All 4 diagnostic assays have been found to have comparable results (Table 1). The sensitivity of Spec cPL (or cPL) has been shown to be higher in dogs with increasing histologic severity.23,32,37

No diagnostic test is 100% sensitive or specific, and the clinical diagnosis should be interpreted in conjunction with the signalment, history, physical examination, CBC and serum biochemistry results, and abdominal ultrasonography findings.9,23,43 Up to 78% of dogs with upper gastrointestinal obstruction may have an elevated cPL, possibly due to increased leakage of immunoassay-positive lipase into the circulation.9 The Precision PSL assay is not specific for pancreatic lipase; therefore, its results may show increased levels in conditions other than pancreatitis.9


Histopathology has been previously considered the gold standard for the diagnosis of pancreatitis.16 This is somewhat inaccurate, as microscopic evidence of pancreatic inflammation does not always translate to clinical presentation or signs. Also, with localized inflammation, representative pathologic samples may not be collected, and the procedure itself is considered invasive, expensive, and not without complications.


Pancreatic cytology is gaining popularity in veterinary medicine. It is relatively noninvasive and has good diagnostic yield, with relatively few complications.44-46 Further studies are needed in veterinary medicine to fully evaluate this technique as a diagnostic tool in the diagnosis of acute pancreatitis. At the author’s institution, fine-needle aspiration of the pancreas is performed to differentiate between pancreatic neoplasia (primary or metastatic) and acute pancreatitis.


The diagnosis of acute pancreatitis can be difficult due to the variable and nonspecific spectrum of clinical presentation. A detailed medical history should be initially obtained, with the diagnosis being made based on a combination of presenting clinical signs, serology, abdominal ultrasonography findings, and response to medical therapy. In addition, highly specific and sensitive tests, like cPL, can be used to differentiate acute pancreatitis from other diseases causing similar clinical signs in dogs. Severe acute pancreatitis is often associated with serious systemic complications that, if not accurately recognized and treated aggressively early in the course of the disease, may lead to death.19


1. Watson P. Pancreatitis in dogs and cats: definitions and pathophysiology. J Small Anim Pract 2015;56(1):3-12.

2. Jensen KB, Chan DL. Nutritional management of acute pancreatitis in dogs and cats. J Vet Emerg Crit Care (San Antonio) 2014;24(3):240-250.

3. Mansfield C. Acute pancreatitis in dogs: advances in understanding, diagnostics, and treatment. Top Companion Anim Med 2012;27(3):123-132.

4. Rademacher N, Schur D, Gaschen F, et al. Contrast-enhanced ultrasonography of the pancreas in healthy dogs and in dogs with acute pancreatitis. Vet Radiol Ultrasound 2016;57(1):58-64.

5. Harris JP, Parnell NK, Griffith EH, et al. Retrospective evaluation of the impact of early enteral nutrition on clinical outcomes in dogs with pancreatitis: 34 cases (2010-2013). J Vet Emerg Crit Care (San Antonio) 2017;27(4):425-433.

6. Hess RS, Saunders HM, Van Winkle TJ, et al. Clinical, clinicopathologic, radiographic, and ultrasonographic abnormalities in dogs with fatal acute pancreatitis: 70 cases (1986-1995). JAVMA 1998;213(5):665-670.

7. Kook PH, Kohler N, Hartnack S, et al. Agreement of serum Spec cPL with the 1,2-o-dilauryl-rac-glycero glutaric acid-(6′-methylresorufin) ester (DGGR) lipase assay and pancreatic ultrasonography in dogs with suspected pancreatitis. J Vet Intern Med 2014;28(3):863-870.

8. Fabres V, Dossin O, Reif C, et al. Development and validation of a novel clinical scoring system for short-term prediction of death in dogs with acute pancreatitis. J Vet Intern Med 2019;33(2):499-507.

9. Cridge H, MacLeod AG, Pachtinger GE, et al. Evaluation of SNAP cPL, Spec cPL, VetScan cPL Rapid Test, and Precision PSL assays for the diagnosis of clinical pancreatitis in dogs. J Vet Intern Med 2018;32(2):658-664.

10. Sato T, Ohno K, Tamamoto T, et al. Assessment of severity and changes in C-reactive protein concentration and various biomarkers in dogs with pancreatitis. J Vet Med Sci 2017;79(1):35-40.

11. Marchetti V, Gori E, Lippi I, et al. Elevated serum creatinine and hyponatremia as prognostic factors in canine acute pancreatitis.
Aust Vet J 2017;95(11):444-447.

12. French JM, Twedt DC, Rao S, Marolf AJ. Computed tomographic angiography and ultrasonography in the diagnosis and evaluation of acute pancreatitis in dogs. J Vet Intern Med 2019;33(1):79-88.

13. Mansfield C, James FE, Robertson ID. Development of a clinical severity index for dogs with acute pancreatitis. JAVMA 2008;233(6):936-944.

14. Cook AK, Breitschwerdt EB, Levine JF, et al. Risk factors associated with acute pancreatitis in dogs: 101 cases (1985-1990). JAVMA 1993;203(5):673-679.

15. Mansfield C. Pathophysiology of acute pancreatitis: potential application from experimental models and human medicine to dogs.
J Vet Intern Med 2012;26(4):875-887.

16. Xenoulis PG. Diagnosis of pancreatitis in dogs and cats. J Small Anim Pract 2015;56(1):13-26.

17. Schaer MA. A clinicopathologic survey of acute pancreatitis in 30 dogs and 5 cats. JAAHA 1979;15:681-687.

18. Kalli I, Adamama-Moraitou K, Rallis TS. Acute pancreatitis in dogs: a review article. EJCAP 2009;19:147-155.

19. Mansfield C, Beths T. Management of acute pancreatitis in dogs: a critical appraisal with focus on feeding and analgesia. J Small Anim Pract 2015;56(1):27-39.

20. Vrolyk V, Wobeser BK, Al-Dissi AN, et al. Lung inflammation associated with clinical acute necrotizing pancreatitis in dogs. Vet Pathol 2017;54(1):129-140.

21. Gori E, Lippi I, Guidi G, et al. Acute pancreatitis and acute kidney injury in dogs. Vet J 2019;245:77-81.

22. Okanishi H, Nagata T, Nakane S, Watari T. Comparison of initial treatment with and without corticosteroids for suspected acute pancreatitis in dogs. J Small Anim Pract 2019;60(5):298-304.

23. Haworth MD, Hosgood G, Swindells KL, Mansfield CS. Diagnostic accuracy of the SNAP and Spec canine pancreatic lipase tests for pancreatitis in dogs presenting with clinical signs of acute abdominal disease. J Vet Emerg Crit Care (San Antonio) 2014;24(2):135-143.

24. Weatherton LK, Streeter EM. Evaluation of fresh frozen plasma administration in dogs with pancreatitis: 77 cases (1995-2005).
J Vet Emerg Crit Care (San Antonio) 2009;19(6):617-622.

25. Yuki M, Hirano T, Nagata N, et al. Clinical utility of diagnostic laboratory tests in dogs with acute pancreatitis: a retrospective investigation in a primary care hospital. J Vet Intern Med 2016;30(1):116-122.

26. Watson PJ, Archer J, Roulois AJ, et al. Observational study of 14 cases of chronic pancreatitis in dogs. Vet Rec 2010;167(25):968-976.

27. Lem KY, Fosgate GT, Norby B, Steiner JM. Associations between dietary factors and pancreatitis in dogs. JAVMA 2008;233(9):1425-1431.

28. Bishop MA, Xenoulis PG, Levinski MD, et al. Identification of variants of the SPINK1 gene and their association with pancreatitis in miniature schnauzers. Am J Vet Res 2010;71(5):527-533.

29. Bishop MA, Steiner JM, Moore LE, et al. Evaluation of the cationic trypsinogen gene for potential mutations in miniature schnauzers with pancreatitis. Can J Vet Res 2004;68(4):315-318.

30. Furrow E, Armstrong PJ, Patterson EE. High prevalence of the c.74A>C SPINK1 variant in miniature and standard schnauzers. J Vet Intern Med 2012;26(6):1295-1299.

31. Gibbs C, Denny HR, Minter HM, Pearson H. Radiological features of inflammatory conditions of the canine pancreas. J Small Anim Pract 1972;13:531-544.

32. Steiner JM, Newman S, Xenoulis PG, et al. Sensitivity of serum markers for pancreatitis in dogs with macroscopic evidence of pancreatitis.
Vet Ther 2008;9(4):263-273.

33. Hecht S, Henry G. Sonographic evaluation of the normal and abnormal pancreas. Clin Tech Small Anim Pract 2007;22(3):115-121.

34. Lim S, Nakamura K, Morishita K, et al. Qualitative and quantitative contrast enhanced ultrasonography of the pancreas using bolus injection and continuous infusion methods in normal dogs. J Vet Med Sci 2013;75(12):1601-1607.

35. Lidbury JA, Suchodolski JS. New advances in the diagnosis of canine and feline liver and pancreatic disease. Vet J 2016;215:87-95.

36. Adrian AM, Twedt DC, Kraft SL, Marolf AJ. Computed tomographic angiography under sedation in the diagnosis of suspected canine pancreatitis: a pilot study. J Vet Intern Med 2015;29(1):97-103.

37. Trivedi S, Marks SL, Kass PH, et al. Sensitivity and specificity of canine pancreas-specific lipase (cPL) and other markers for pancreatitis in 70 dogs with and without histopathologic evidence of pancreatitis. J Vet Intern Med 2011;25(6):1241-1247.

38. Steiner JM, Williams DA. Development and validation of a radioimmunoassay for the measurement of canine pancreatic lipase immunoreactivity in serum of dogs. Am J Vet Res 2003;64(10):1237-1241.

39. McCord K, Morley PS, Armstrong J, et al. A multi-institutional study evaluating the diagnostic utility of the spec cPL™ and SNAP® cPL™ in clinical acute pancreatitis in 84 dogs. J Vet Intern Med 2012;26(4):888-896.

40. Steiner JM, Berridge BR, Wojcieszyn J, et al. Cellular immunolocalization of gastric and pancreatic lipase in various tissues obtained from dogs. Am J Vet Res 2002;63:722-727.

41. Steiner JM, Teague SR, Williams DA. Development and analytic validation of an enzyme-linked immunosorbent assay for the measurement of canine pancreatic lipase immunoreactivity in serum. Can J Vet Res 2003;67(3):175-182.

42. Beall MJ, Cahill R, Pigeon K, et al. Performance validation and method comparison of an in-clinic enzyme-linked immunosorbent assay for the detection of canine pancreatic lipase. J Vet Diagn Invest 2011;23(1):115-119.

43. Graca R, Messick J, McCullough S, et al. Validation and diagnostic efficacy of a lipase assay using the substrate 1,2-o-dilauryl-rac-glycero glutaric acid-(6’ methyl resorufin)-ester for the diagnosis of acute pancreatitis in dogs. Vet Clin Pathol 2005;34(1):39-43.

44. Kook PH, Baloi P, Ruetten M, et al. Feasibility and safety of endoscopic ultrasound-guided fine needle aspiration of the pancreas in dogs. J Vet Intern Med 2012;26(3):513-517.

45. Cordner AP, Sharkey LC, Armstrong PJ, et al. Cytologic findings and diagnostic yield in 92 dogs undergoing fine-needle aspiration of the pancreas. J Vet Diagn Invest 2015;27(2):236-240.

46. Cordner AP, Armstrong PJ, Newman SJ, et al. Effect of pancreatic tissue sampling on serum pancreatic enzyme levels in clinically healthy dogs. J Vet Diagn Invest 2010;22(5):702-707 Protection Status
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resources offered in a variety of formats including videos, podcasts, webinars and more.</div></label> </li><li class='gchoice_6_15_6'> <input name='input_15.6' type='checkbox' value='Partner Emails&lt;br&gt;&lt;div style=&quot;font-size: 12px;color: #808080&quot;&gt;Exclusive deals and information from our partners.&lt;/div&gt;' id='choice_6_15_6' /> <label for='choice_6_15_6' id='label_6_15_6'>Partner Emails<br><div style="font-size: 12px; color: #808080;">Exclusive deals and information from our partners.</div></label> </li></ul></div></li><li id='field_6_19' class='gfield gfield_html gfield_html_formatted field_sublabel_below field_description_below gfield_visibility_visible' ><br></li><li id='field_6_22' class='gfield field_sublabel_below field_description_below gfield_visibility_visible' ><label class='gfield_label' >Do you want to be added to our postal mailing list?</label><div class='ginput_container ginput_container_checkbox'><ul class='gfield_checkbox' id='input_6_22'><li class='gchoice_6_22_1'> <input name='input_22.1' type='checkbox' value='Yes, I love mail!' id='choice_6_22_1' /> <label for='choice_6_22_1' id='label_6_22_1'>Yes, I love mail!</label> </li><li class='gchoice_6_22_2'> <input name='input_22.2' type='checkbox' value='No thank you.' id='choice_6_22_2' /> <label for='choice_6_22_2' id='label_6_22_2'>No thank you.</label> </li></ul></div></li><li id='field_6_10' class='gfield gfield_contains_required field_sublabel_below field_description_below gfield_visibility_visible' ><label class='gfield_label gfield_label_before_complex' >Please provide your mailing address below.<span class='gfield_required'>*</span></label> <div class='ginput_complex ginput_container has_street has_street2 has_city has_state has_zip has_country ginput_container_address' id='input_6_10' > <span class='ginput_full address_line_1' id='input_6_10_1_container' > <input type='text' name='input_10.1' id='input_6_10_1' value='' aria-required="true"/> <label for='input_6_10_1' id='input_6_10_1_label' >Street Address</label> </span><span class='ginput_full address_line_2' id='input_6_10_2_container' > <input type='text' name='input_10.2' id='input_6_10_2' value='' /> <label for='input_6_10_2' id='input_6_10_2_label' >Address Line 2</label> </span><span class='ginput_left address_city' id='input_6_10_3_container' > <input type='text' name='input_10.3' id='input_6_10_3' value='' aria-required="true"/> <label for='input_6_10_3' id='input_6_10_3_label' >City</label> </span><span class='ginput_right address_state' id='input_6_10_4_container' > <input type='text' name='input_10.4' id='input_6_10_4' value='' aria-required="true"/> <label for='input_6_10_4' id='input_6_10_4_label' >State / Province / Region</label> </span><span class='ginput_left address_zip' id='input_6_10_5_container' > <input type='text' name='input_10.5' id='input_6_10_5' value='' aria-required="true"/> <label for='input_6_10_5' id='input_6_10_5_label' >ZIP / Postal Code</label> </span><span class='ginput_right address_country' id='input_6_10_6_container' > <select name='input_10.6' id='input_6_10_6' aria-required="true"><option value='' selected='selected'></option><option value='Afghanistan' >Afghanistan</option><option value='Åland Islands' >Åland Islands</option><option value='Albania' >Albania</option><option value='Algeria' >Algeria</option><option value='American Samoa' >American Samoa</option><option value='Andorra' >Andorra</option><option value='Angola' >Angola</option><option value='Anguilla' >Anguilla</option><option value='Antarctica' >Antarctica</option><option value='Antigua and Barbuda' >Antigua and Barbuda</option><option value='Argentina' >Argentina</option><option value='Armenia' >Armenia</option><option value='Aruba' >Aruba</option><option value='Australia' >Australia</option><option value='Austria' >Austria</option><option value='Azerbaijan' >Azerbaijan</option><option value='Bahamas' >Bahamas</option><option value='Bahrain' >Bahrain</option><option value='Bangladesh' >Bangladesh</option><option value='Barbados' >Barbados</option><option value='Belarus' >Belarus</option><option value='Belgium' >Belgium</option><option value='Belize' >Belize</option><option value='Benin' >Benin</option><option value='Bermuda' >Bermuda</option><option value='Bhutan' >Bhutan</option><option value='Bolivia' >Bolivia</option><option value='Bonaire, Sint Eustatius and Saba' >Bonaire, Sint Eustatius and Saba</option><option value='Bosnia and Herzegovina' >Bosnia and Herzegovina</option><option value='Botswana' >Botswana</option><option value='Bouvet Island' >Bouvet Island</option><option value='Brazil' >Brazil</option><option value='British Indian Ocean Territory' >British Indian Ocean Territory</option><option value='Brunei Darussalam' >Brunei Darussalam</option><option value='Bulgaria' >Bulgaria</option><option value='Burkina Faso' >Burkina Faso</option><option value='Burundi' >Burundi</option><option value='Cambodia' >Cambodia</option><option value='Cameroon' >Cameroon</option><option value='Canada' >Canada</option><option value='Cape Verde' >Cape Verde</option><option value='Cayman Islands' >Cayman Islands</option><option value='Central African Republic' >Central African Republic</option><option value='Chad' >Chad</option><option value='Chile' >Chile</option><option value='China' >China</option><option value='Christmas Island' >Christmas Island</option><option value='Cocos Islands' >Cocos Islands</option><option value='Colombia' >Colombia</option><option value='Comoros' >Comoros</option><option value='Congo, Democratic Republic of the' >Congo, Democratic Republic of the</option><option value='Congo, Republic of the' >Congo, Republic of the</option><option value='Cook Islands' >Cook Islands</option><option value='Costa Rica' >Costa Rica</option><option value='Côte d&#039;Ivoire' >Côte d&#039;Ivoire</option><option value='Croatia' >Croatia</option><option value='Cuba' >Cuba</option><option value='Curaçao' >Curaçao</option><option value='Cyprus' >Cyprus</option><option value='Czech Republic' >Czech Republic</option><option value='Denmark' >Denmark</option><option value='Djibouti' >Djibouti</option><option value='Dominica' >Dominica</option><option value='Dominican Republic' >Dominican Republic</option><option value='Ecuador' >Ecuador</option><option value='Egypt' >Egypt</option><option value='El Salvador' >El Salvador</option><option value='Equatorial Guinea' >Equatorial Guinea</option><option value='Eritrea' >Eritrea</option><option value='Estonia' >Estonia</option><option value='Eswatini (Swaziland)' >Eswatini (Swaziland)</option><option value='Ethiopia' >Ethiopia</option><option value='Falkland Islands' >Falkland Islands</option><option value='Faroe Islands' >Faroe Islands</option><option value='Fiji' >Fiji</option><option value='Finland' >Finland</option><option value='France' >France</option><option value='French Guiana' >French Guiana</option><option value='French Polynesia' >French Polynesia</option><option value='French Southern Territories' >French Southern Territories</option><option value='Gabon' >Gabon</option><option value='Gambia' >Gambia</option><option value='Georgia' >Georgia</option><option value='Germany' >Germany</option><option value='Ghana' >Ghana</option><option value='Gibraltar' >Gibraltar</option><option value='Greece' >Greece</option><option value='Greenland' >Greenland</option><option value='Grenada' >Grenada</option><option value='Guadeloupe' >Guadeloupe</option><option value='Guam' >Guam</option><option value='Guatemala' >Guatemala</option><option value='Guernsey' >Guernsey</option><option value='Guinea' >Guinea</option><option value='Guinea-Bissau' >Guinea-Bissau</option><option value='Guyana' >Guyana</option><option value='Haiti' >Haiti</option><option value='Heard and McDonald Islands' >Heard and McDonald Islands</option><option value='Holy See' >Holy See</option><option value='Honduras' >Honduras</option><option value='Hong Kong' >Hong Kong</option><option value='Hungary' >Hungary</option><option value='Iceland' >Iceland</option><option value='India' >India</option><option value='Indonesia' >Indonesia</option><option value='Iran' >Iran</option><option value='Iraq' >Iraq</option><option value='Ireland' >Ireland</option><option value='Isle of Man' >Isle of Man</option><option value='Israel' >Israel</option><option value='Italy' >Italy</option><option value='Jamaica' >Jamaica</option><option value='Japan' >Japan</option><option value='Jersey' >Jersey</option><option value='Jordan' >Jordan</option><option value='Kazakhstan' >Kazakhstan</option><option value='Kenya' >Kenya</option><option value='Kiribati' >Kiribati</option><option value='Kuwait' >Kuwait</option><option value='Kyrgyzstan' >Kyrgyzstan</option><option value='Lao People&#039;s Democratic Republic' >Lao People&#039;s Democratic Republic</option><option value='Latvia' >Latvia</option><option value='Lebanon' >Lebanon</option><option value='Lesotho' >Lesotho</option><option value='Liberia' >Liberia</option><option value='Libya' >Libya</option><option value='Liechtenstein' >Liechtenstein</option><option value='Lithuania' >Lithuania</option><option value='Luxembourg' >Luxembourg</option><option value='Macau' >Macau</option><option value='Macedonia' >Macedonia</option><option value='Madagascar' >Madagascar</option><option value='Malawi' >Malawi</option><option value='Malaysia' >Malaysia</option><option value='Maldives' >Maldives</option><option value='Mali' >Mali</option><option value='Malta' >Malta</option><option value='Marshall Islands' >Marshall Islands</option><option value='Martinique' >Martinique</option><option value='Mauritania' >Mauritania</option><option value='Mauritius' >Mauritius</option><option value='Mayotte' >Mayotte</option><option value='Mexico' >Mexico</option><option value='Micronesia' >Micronesia</option><option value='Moldova' >Moldova</option><option value='Monaco' >Monaco</option><option value='Mongolia' >Mongolia</option><option value='Montenegro' >Montenegro</option><option value='Montserrat' >Montserrat</option><option value='Morocco' >Morocco</option><option value='Mozambique' >Mozambique</option><option value='Myanmar' >Myanmar</option><option value='Namibia' >Namibia</option><option value='Nauru' >Nauru</option><option value='Nepal' >Nepal</option><option value='Netherlands' >Netherlands</option><option value='New Caledonia' >New Caledonia</option><option value='New Zealand' >New Zealand</option><option value='Nicaragua' >Nicaragua</option><option value='Niger' >Niger</option><option value='Nigeria' >Nigeria</option><option value='Niue' >Niue</option><option value='Norfolk Island' >Norfolk Island</option><option value='North Korea' >North Korea</option><option value='Northern Mariana Islands' >Northern Mariana Islands</option><option value='Norway' >Norway</option><option value='Oman' >Oman</option><option value='Pakistan' >Pakistan</option><option value='Palau' >Palau</option><option value='Palestine, State of' >Palestine, State of</option><option value='Panama' >Panama</option><option value='Papua New Guinea' >Papua New Guinea</option><option value='Paraguay' >Paraguay</option><option value='Peru' >Peru</option><option value='Philippines' >Philippines</option><option value='Pitcairn' >Pitcairn</option><option value='Poland' >Poland</option><option value='Portugal' >Portugal</option><option value='Puerto Rico' >Puerto Rico</option><option value='Qatar' >Qatar</option><option value='Réunion' >Réunion</option><option value='Romania' >Romania</option><option value='Russia' >Russia</option><option value='Rwanda' >Rwanda</option><option value='Saint Barthélemy' >Saint Barthélemy</option><option value='Saint Helena' >Saint Helena</option><option value='Saint Kitts and Nevis' >Saint Kitts and Nevis</option><option value='Saint Lucia' >Saint Lucia</option><option value='Saint Martin' >Saint Martin</option><option value='Saint Pierre and Miquelon' >Saint Pierre and Miquelon</option><option value='Saint Vincent and the Grenadines' >Saint Vincent and the Grenadines</option><option value='Samoa' >Samoa</option><option value='San Marino' >San Marino</option><option value='Sao Tome and Principe' >Sao Tome and Principe</option><option value='Saudi Arabia' >Saudi Arabia</option><option value='Senegal' >Senegal</option><option value='Serbia' >Serbia</option><option value='Seychelles' >Seychelles</option><option value='Sierra Leone' >Sierra Leone</option><option value='Singapore' >Singapore</option><option value='Sint Maarten' >Sint Maarten</option><option value='Slovakia' >Slovakia</option><option value='Slovenia' >Slovenia</option><option value='Solomon Islands' >Solomon Islands</option><option value='Somalia' >Somalia</option><option value='South Africa' >South Africa</option><option value='South Georgia' >South Georgia</option><option value='South Korea' >South Korea</option><option value='South Sudan' >South Sudan</option><option value='Spain' >Spain</option><option value='Sri Lanka' >Sri Lanka</option><option value='Sudan' >Sudan</option><option value='Suriname' >Suriname</option><option value='Svalbard and Jan Mayen Islands' >Svalbard and Jan Mayen Islands</option><option value='Sweden' >Sweden</option><option value='Switzerland' >Switzerland</option><option value='Syria' >Syria</option><option value='Taiwan' >Taiwan</option><option value='Tajikistan' >Tajikistan</option><option value='Tanzania' >Tanzania</option><option value='Thailand' >Thailand</option><option value='Timor-Leste' >Timor-Leste</option><option value='Togo' >Togo</option><option value='Tokelau' >Tokelau</option><option value='Tonga' >Tonga</option><option value='Trinidad and Tobago' >Trinidad and Tobago</option><option value='Tunisia' >Tunisia</option><option value='Turkey' >Turkey</option><option value='Turkmenistan' >Turkmenistan</option><option value='Turks and Caicos Islands' >Turks and Caicos Islands</option><option value='Tuvalu' 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