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Mobility Is Key to a Healthy Quality of Life for Pets

Add Synovi G4® – powerful support for healthy hips and joints – as part of your multi-modal approach to care.

Mobility Is Key to a Healthy Quality of Life for Pets

This sponsored article is brought to you by Elanco.

As dogs live longer, keeping them mobile and flexible is one of the great challenges faced in animal medicine. Although mobility issues disproportionately affect older patients, their onset typically begins at an early age in dogs – the result of wear and tear on joints.

Because this type of discomfort is nonadaptive, it tends to grow worse out of proportion with the initial insult, becoming a downward, maladaptive spiral.

The only way to combat this is to get in front of it with early intervention and lifelong support. A forward-thinking joint supplement like Synovi G4® from Elanco can help as part of your long-term management strategy.

Synovi G4® Active Ingredients
  • Helps ease occasional joint stiffness due to normal daily exercise and activity
  • Protect against free radical damage, especially in joints

Each 7.2 gram soft chew contains:
Glucosamine HCl (shellfish) 450 mg
Methylsulfonylmethane (MSM) 400 mg
Creatine Monohydrate 250 mg
Boswellia serrata Extract (containing 65% Boswellic Acids) 150 mg
Perna canaliculus (Green-Lipped Mussel) 150 mg
Proprietary blend of Dicalcium Phosphate, Citrus Bioflavonoids, Ascorbic Acid (Vitamin C), Manganese Sulfate, Grape Seed Extract, Zinc Sulfate and Alpha Lipoic Acid 148 mg
Curcuma longa (Turmeric) 50 mg
Selenium (as L-Selenomethionine) 10 mcg
D-Alpha Tocopheryl Acetate (Vitamin E) 25 IU

Veterinarian-formulated pet supplements.

Increasingly, evidence-based data justifies a potent role for supplements as part of a multi-modal approach with the focus on supporting healthy joint cartilage throughout a pet’s life.

Articular cartilage is composed of three main components:

Extracellular matrix (ECM) – made up of collagen fibers and proteoglycans (PG), which
serve to trap water
Chondrocytes – function to synthesize the components of the ECM and also produce the
enzymes that regulate cartilage anabolism
Water – makes up 70% of cartilage and gives it unique shock-absorbing biomechanical
properties

In a normal joint, there is a balance between the synthetic and degradative activity aided by various cytokines and growth factors. When catabolic processes outweigh anabolic, marked by increases in degradative enzymes and proinflammatory cytokines, this leads to reduced PG concentration and reduced ability of the ECM to retain water.

Healthy synovial fluid, viscous solution found in the cavities of synovial joints, also plays a key role in joint health by reducing friction between the articular cartilage during movement.

Clearly, maintaining healthy joint cartilage and synovial fluid is key.

Backed by science.

While supplements, particularly glucosamine and chondroitin-based products, have long been recommended, growing scientific evidence is now substantiating the myriad anecdotal claims of efficacy showing that the presence of certain compounds in the joint prior to or at the time of joint insult can help support healthy articular cartilage.

Beyond the basics.

For joint support that goes beyond just glucosamine and chondroitin, Synovi G4® helps support joint function and flexibility, healthy cartilage, connective tissue and synovial fluid. This tried-and-true formulation is based on the veterinary favorite Synovi G3® formula base, which includes glucosamine, green-lipped mussel (Perna canaliculus) and omega-3 fatty acids. With the addition of Curcuma longa and Boswellia serrata for additional mobility and antioxidant support, Synovi® G4 is powerful support.

Glucosamine + Boswellia for joint support and normal inflammatory response

MSM + Turmeric for free radical scavenging and antioxidant support

Green-Lipped Mussel (a natural source of chondroitin) provides the building blocks for healthy joints

Creatine Monohydrate for muscle tone and contraction support

green lipped mussel pets

Why Green-Lipped Mussel?

Green-lipped mussels contain the same powerful Omega-3 fatty acids (EPA and DHA)
commonly found in fish oil. In addition, they also have been shown to include
eicosatetraenoic acid (ETA) and glycosaminoglycans for a more complete source.

Stock smart with one product for all sizes.

Weight                     Daily Amount

Under 15 lb             1⁄2 Chew Every Other Day
16 -30 lb                  1⁄2 Chew Daily
31 -60 lb                  1 Chew Daily
61 -100 lb                2 Chews Daily
Over 100 lb             2 1⁄2 Chews Daily

Chicken-flavored soft chew that can be given during or after mealtime for easy administration.

Formulation matters.

At Elanco, we believe that formulation matters. We pay careful attention to what is and what isn’t in our supplements. That’s why our products are grounded in science. It’s why you’ll find a quality seal from the National Animal Supplement Council (NASC) on every label. The quality seal identifies products from companies that are committed to going the extra mile to ensure quality, vigilance and continuous improvement for the well-being of companion animals. And it’s why you can confidently recommend Elanco Pet Supplements for the dogs and cats in your care.

Support mobility in your canine patients now with Synovi® G4.

Mobility issues will affect 20% or more of your canine patients. It can slowly progress to a point in which articular cartilage cannot be restored.

Early recognition and initiation of powerful joint support, as well as ongoing monitoring of patients, can result in more consistent success in supporting healthy joint function, comfort and mobility.


WARNINGS: For animal use only. Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately.

CAUTIONS: Safe use in pregnant animals or animals intended for breeding has not been proven. If lameness worsens, discontinue use and contact your veterinarian. Administer during or after the animal has eaten to reduce incidence of gastrointestinal upset.

Synovi G4, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. ©2021 Elanco or its affiliates. PM-US-21-0066

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