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T8 Keto® – Flush Patented Formula, Proven Performance

Consider T8 Keto® as a complement to your current ear treatment regimen.

T8 Keto® – Flush Patented Formula, Proven Performance
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Many dogs are susceptible to developing dirty or infected ears. When they get an ear infection, this can complicate treatment.

Ceruminolytic Activity

Common pathogens like Pseudomonas aeruginosa and Malassezia pachydermatis actively work against your treatment protocol by creating debris, wax and other discharge that act as a barrier.

The cleaning action of T8 Keto® breaks apart and removes:

  • Excessive wax and ceruminous discharge
  • Inflammatory debris
  • Biofilms and pus

This allows topical medications to reach deep into the ear canal, including the horizontal  canal where most of the infection typically resides.

T8 Keto® promotes ear health and the normalization of the ear canal, including epithelial migration, which is key to restoring the cell layer that helps prevent the entry of pathogens and leakage of fluids.

Ketoconazole and Tris-EDTA

T8 Keto® offers Tris-EDTA and ketoconazole in a patented alkaline, water-based formulation combined with mild surfactants for gentle cleansing and flushing of patients’ ears.

Bacteria Potentiating Tris-EDTA

Tris-EDTA damages and destabilizes bacterial cell walls, especially gram-negatives. This, in turn, increases susceptibility of bacteria to antimicrobial therapies, particularly fluoroquinolones, aminoglycosides and silver sulfadiazine.1,2

Kills Microorganisms Fast

T8 Keto® provides 60-second rapid kill of common ear pathogens such as Malassezia pachydermatis and Pseudomonas aeruginosa in vitro.*3 It also has demonstrated in vitro activity against Staphylococcus spp., Staphylococcus pseudintermedius, Proteus and β-hemolytic streptococcus.*1

Nonirritating, pH-Appropriate Base

T8 Keto® has an alkaline (pH 8.5) base. This helps maximize Tris-EDTA’s activity. And because fluoroquinolones and aminoglycosides work better in an alkaline environment, they help set your treatment protocol up for success.4 

This formula does not sting or burn, making it potentially more pleasant for the patient, aiding in compliance.

The Benefits of Benzyl Alcohol

Benzyl alcohol prevents product contamination after repeated use in infected ears. It also provides antiseptic activity against gram-positive cocci and gram-negative rods.5

To learn more about adding T8 Keto® to complement  your treatment regimen, contact your Elanco sales representative or Customer Service at (800) 633-3796.


CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. For topical use on dogs, cats and horses. Avoid contact with eyes. If eye contact occurs or skin irritation develops, rinse thoroughly with water, discontinue use and contact your veterinarian.

WARNING: Keep out of reach of children. Not for human use.

DVM, DVM and Design, T8 Keto, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

©2021 Elanco or its affiliates. PM-US-21-1252

References

*The clinical significance of in vitro data has not been determined.

1Cole LK, Luu DH, Rajala-Schultz PJ, et al. Am J Vet Res. 2006;67:1040-4.

2Farca AM, Piromalli G, Maffei F, et al. J Small Anim Pract. 1997;38(6): 243-5.

3Elanco Animal Health. Data on file.

4Bloom P. In Proceedings. Wild West Veterinary Conference. 2013.

5Lucchini JJ, Corre J, Cremieux A. Antibacterial activity of phenolic compounds and aromatic alcohols. Res Microbiol. 1990;141:499-510

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