Treatment of Pituitary-Dependent Hyperadrenocorticism
Pituitary-dependent hyperadrenocorticism (PDH) is the most common cause of spontaneous Cushing’s syndrome in dogs. It is the result of the inappropriate secretion of adrenocorticotropic hormone (ACTH) by a pituitary adenoma.
Diagnosis and Management of Hypoadrenocorticism in Dogs
Primary hypoadrenocorticism, also known as Addison’s disease, is a syndrome caused by bilateral dysfunction of the adrenal cortices. Diagnosis can be difficult and management varies between Addison’s disease and atypical Addison’s disease.
Managing Feline Diabetes Mellitus
Diabetes mellitus (DM) is a common endocrinopathy in cats, with reported prevalence rates ranging from 0.4% to 1.2%. Factors related to the patient’s diet and adiposity and the presence of comorbid conditions (e.g., acromegaly, pancreatitis) likely contribute to the pathogenesis of feline DM as well as influence response to therapy and chances for achieving remission.
Canine Hypothyroidism: Diagnosis and Treatment
Hypothyroidism is a common endocrine disease of dogs. Measurement of T4 concentration is helpful to rule out hypothyroidism but should not be solely relied on to confirm the diagnosis.
The Diagnosis of Canine Hyperadrenocorticism
Diagnosis of canine hyperadrenocorticism (HAC) or Cushing’s syndrome is difficult in some cases due to factors such as the presence of nonadrenal illness and limitations in the tests.
An Uncontrolled Diabetic Dog
Six months before presentation, Buster was presented to his primary veterinarian for polyuria, polydipsia, and weight loss. Physical examination and complete blood count (CBC) were unremarkable, while the serum biochemical profile demonstrated: mildly increased alkaline phosphatase (ALP)…
Canine Insulinoma: Diagnosis, Treatment, & Staging
Aside from a histologic confirmation of insulinoma, no currently available diagnostic test provides a definitive diagnosis of insulinoma. Existing techniques may help increase suspicion for an insulin-secreting tumor but, with most diagnostic testing, it is imperative to interpret all results in the context of the coexisting clinical signs.
The ADR (Ain’t Doing Right) Dog: Endocrine Emergencies
The owner reported that Lucky vomited in the car a week earlier when coming home from the groomer. Over the past week, Lucky’s appetite diminished but she seemed thirstier. Lucky had become progressively more lethargic and anorectic over the past 2 days….
Canine Pituitary Dependent Hyperadrenocorticism Series, Part 3: Current & Investigative Options for Therapy
Canine pituitary dependent hyperadrenocorticism (PDH), also known as Cushing’s disease, is a common endocrine disorder in older dogs. This disorder is caused by a pituitary adenoma (PA) that secretes inappropriate amounts of adrenocorticotropic hormone (ACTH)…