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May/June 2019

Column

Alfaxalone: An Old Drug in a New Formulation

Alfaxalone has been used to induce general anesthesia for many years, but only recently has a new formulation with preservatives become available in the United States. This formulation has a shelf life of 28 days after first use. It is approved for IV administration to induce and maintain general anesthesia in dogs and cats; however, it is also used via the IM route for induction and sedation (off label).

Features

Managing Feline Diabetes Mellitus

Diabetes mellitus (DM) is a common endocrinopathy in cats, with reported prevalence rates ranging from 0.4% to 1.2%. Factors related to the patient’s diet and adiposity and the presence of comorbid conditions (e.g., acromegaly, pancreatitis) likely contribute to the pathogenesis of feline DM as well as influence response to therapy and chances for achieving remission.

Essentials

Tick-borne Rickettsial Infections of Dogs

Rickettsial organisms are small, obligate intracellular bacteria in the order Rickettsiales. Two families—Anaplasmataceae and Rickettsiaceae—contain species that infect dogs. These pathogens are transmitted by a variety of tick vectors, maintained in wildlife and domestic reservoirs, and can cause clinical disease in humans, dogs, and other domestic animals. This article discusses the basic epidemiology, clinical presentation, diagnosis, and treatment of canine ehrlichiosis, anaplasmosis, and Rocky Mountain spotted fever (RMSF).

Clinical Insights

Evaluating Fresh Diets in Practice

Dietary trends for dogs and cats closely mirror those of their owners, and it is no surprise that home-prepared meals and their commercialized derivatives are now encountered in practice. These diets pose potential benefits as well as challenges, and clients increasingly expect veterinarians to demonstrate knowledge of them.

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