Grapiprant for Control of Osteoarthritis Pain in Dogs
For centuries, nonsteroidal anti-inflammatory drugs (NSAIDs) have been used for pain control. However, their use has been associated with potentially life-threatening adverse drug events. Grapiprant is a novel drug for treatment of osteoarthritic pain in dogs. Approved in 2016, it is a non-cyclooxygenase (COX)-inhibiting NSAID.
How to Educate Clients About Motion Sickness in Dogs
Motion sickness can afflict any pet during even the shortest of rides. Read more about how to educate clients about the symptoms and treatments for motion sickness with advice from Zoetis Veterinary Medical Lead, Dr. Joyce Login, DVM.
The Use of Capromorelin for the Clinical Problem of Inappetence
Inappetence is a common clinical sign that has an important influence on perceived quality of life and case management in dogs and cats. Capromorelin has the potential to positively affect the clinical management of inappetence and weight loss/cachexia in dogs.
Alfaxalone: An Old Drug in a New Formulation
Alfaxalone has been used to induce general anesthesia for many years, but only recently has a new formulation with preservatives become available in the United States. This formulation has a shelf life of 28 days after first use. It is approved for IV administration to induce and maintain general anesthesia in dogs and cats; however, it is also used via the IM route for induction and sedation (off label).
Mirtazapine: Addressing Appetite in Cats
A review of the studies of oral mirtazapine—which stimulates appetite—and current recommendations for cats, including normal cats, geriatric cats, and cats with kidney or liver disease.
The Therapeutic Power of Monoclonal Antibody Therapy
Biotherapeutics are still relatively new in veterinary medicine. This article reviews biologic therapy as it relates specifically to monoclonal antibodies (mAbs) and covers the only fully licensed and commercially available product, lokivetmab (Cytopoint).
Telmisartan for Treating Systemic Hypertension
A review of the mechanism of action of the angiotensin II receptor blocker telmisartan; plus, its use in veterinary medicine to date.
Gabapentin and Amantadine for Chronic Pain: Is Your Dose Right?
The scientific mechanisms of gabapentin and amantadine support their use as part of analgesic protocols for chronic pain relief in dogs and cats. Each can effectively treat chronic pain, but how do you know when to choose one drug over the other?
Pimobendan and Heart Disease
Pimobendan is a benzimidazole-pyridazinone derivative, labeled for use in dogs to manage congestive heart failure (CHF) resulting from dilated cardiomyopathy (DCM) or degenerative mitral valve disease (DMVD) in the United States. On the basis of its positive inotropic effects combined with arteriovenous dilation, it is classified as an inodilator.1 In this article, we provide relevant …