Pharmacology

Clinical Insights

Grapiprant for Control of Osteoarthritis Pain in Dogs

For centuries, nonsteroidal anti-inflammatory drugs (NSAIDs) have been used for pain control. However, their use has been associated with potentially life-threatening adverse drug events. Grapiprant is a novel drug for treatment of osteoarthritic pain in dogs. Approved in 2016, it is a non-cyclooxygenase (COX)-inhibiting NSAID.

motion sickness

How to Educate Clients About Motion Sickness in Dogs

Motion sickness can afflict any pet during even the shortest of rides. Read more about how to educate clients about the symptoms and treatments for motion sickness with advice from Zoetis Veterinary Medical Lead, Dr. Joyce Login, DVM.

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Alfaxalone: An Old Drug in a New Formulation

Alfaxalone has been used to induce general anesthesia for many years, but only recently has a new formulation with preservatives become available in the United States. This formulation has a shelf life of 28 days after first use. It is approved for IV administration to induce and maintain general anesthesia in dogs and cats; however, it is also used via the IM route for induction and sedation (off label).

Clinical Insights

Pimobendan and Heart Disease

Pimobendan is a benzimidazole-pyridazinone derivative, labeled for use in dogs to manage congestive heart failure (CHF) resulting from dilated cardiomyopathy (DCM) or degenerative mitral valve disease (DMVD) in the United States. On the basis of its positive inotropic effects combined with arteriovenous dilation, it is classified as an inodilator.1 In this article, we provide relevant …

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