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Adrenal Glands: Peaks and Valleys

Hyperadrenocorticism (HAC) - aka Cushing’s disease - in dogs can be a diagnostic and treatment challenge for the veterinary professionals who care for these patients. Hypoadrenocorticism (HOAC) - aka Addison’s disease - cannot typically be cured with medication, but it can be successfully managed. When you have a patient with HAC or HOAC, we hope that you think of Dechra. We want to help you improve the lives of dogs with these conditions. 

Since the launch of Vetoryl® Capsules (trilostane) in 2009 and the launch of Zycortal® Suspension (desoxycorticosterone pivalate injectable suspension) in 2016, Dechra has been a leader in partnering with veterinarians to help dogs with endocrine diseases.


DELIVERING EXCELLENCE:

Vetoryl® Capsules (trilostane) and Zycortal® Suspension(desoxycorticosterone pivalate injectable suspension)

Vetoryl® (trilostane)


Vetoryl

Vetoryl® is indicated for the treatment of pituitary-dependent hyperadrenocorticism

(Cushing’s disease) in dogs and the treatment of hyperadrenocorticism (Cushing’s disease) due to adrenocortical tumor in dogs


Zycortal® (desoxycorticosterone pivalate injectable suspension)


zycortal

Zycortal® is given subcutaneously as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s disease).



RESOURCES, TOOLS AND TIPS

These adrenal diseases are not always easy to diagnose and are sometimes challenging to manage. Below are some great resources for you to help diagnose and manage the diseases in your canine patients.


VET2VET VIDEO CONVERSATION


Does the Glass Slipper Fit? 

An Addisonian Case Study

Click to play

In this Vet2Vet conversation, Dr. Audrey Cook walks us through the evaluation, diagnosis, and treatment of a dog with hypoadrenocorticism.

“Addison’s is so incredibly treatable ... and the long- term diagnosis [for these dogs] is excellent,” says Dr. Cook. 

Watch this episode of Vet2Vet to learn how Dr. Cook makes certain — by trying on “Cinderella’s glass slipper” — that she does not overlook Addison’s in her patients.


 DIGITAL RESOURCES FOR YOUR CLINIC


Vetoryl® - Diagnosis, Treatment and Monitoring of Hyperadrenocorticism

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Zycortal® -Step by Step Diagnosis of Hypoadrenocorticism Flowchart

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Vetoryl® Capsules (Trilostane) Monitoring Form

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Vetoryl® Capsules Brochure for Pet Owners

zycortal pet owner brochure

Zycortal® Brochures for Pet Owners

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Vetoryl® Important Safety Information

As with all drugs, side effects may occur. In field studies and post-approval experience, the most common side effects reported were: anorexia, lethargy/depression, vomiting, diarrhea, elevated liver enzymes, elevated potassium with or without decreased sodium, elevated BUN, decreased Na/K ratio, hypoadrenocorticism, weakness, elevated creatinine, shaking, and renal insufficiency. In some cases, death has been reported as an outcome of these adverse events. VETORYL Capsules are not for use in dogs with primary hepatic or renal disease, or in pregnant dogs. Refer to the prescribing information for complete details or visit www.dechra- us.com.

Zycortal® Important Safety Information

As with all drugs, side effects may occur. In field studies and post-approval experience, the most common side effects reported were: polyuria, polydipsia, depression/lethargy, pain on injection, weight gain, inappropriate urination, alopecia, decreased appetite/anorexia, panting, vomiting, diarrhea, shaking/trembling, polyphagia, urinary tract infection, urinary tract incontinence, anaphylaxis, anemia, restlessness and collapse. Death or euthanasia has been associated with some of the adverse events listed above. ZYCORTAL Suspension should be used with caution in dogs with congestive heart disease, edema, severe renal disease or primary hepatic failure. Dogs presenting in Addisonian crisis must be rehydrated with appropriate intravenous therapy before starting treatment with ZYCORTAL Suspension. Refer to the prescribing information for complete details or visit www.dechra-us.com.

Vetoryl and Zycortal are registered trademarks of Dechra Limited.


LEARN MORE WITH

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DECHRA ACADEMY

Additionally, Dechra offers free endocrinology lessons and free CE credit to veterinarians and

 veterinary technicians.

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