Pharmacology

Proin, which has been shown to improve continence in dogs with USMI, is approved as a chewable tablet in the U.S.

Phenylpropanolamine is effective at improving continence in dogs with USMI, although routine blood pressure monitoring should be performed and special consideration should be taken for animals with behavioral concerns.

Research studies show that DOCP injectable suspension is a safe and effective therapy for dogs with Addison’s disease.

DOCP is a safe and effective mineralocorticoid replacement therapy when used in dogs with primary hypoadrenocorticism. Further research is needed to better characterize clinically appropriate starting doses and evaluate the efficacy of the various dose adjustment and monitoring protocols used in clinical practice. 

Imidacloprid chews, topical solutions, and collars have been shown to treat flea infestations in dogs.

Imidacloprid chews, topical solutions, and collars have been shown to treat flea infestations in dogs.

Convenia's (cefovecin sodium) convenient one-time dosing eliminates reliance on owner compliance while providing efficacy similar to that of traditional oral antibiotic regimens.

Cefovecin sodium provides reliable efficacy for the treatment of canine and feline skin infections, abscesses, and wounds. Its convenient one-time dosing eliminates reliance on owners to maintain medication compliance for days to weeks while providing efficacy similar to that of traditional oral antibiotic regimens.

Nocita (bupivacaine liposome injectable suspension) is a long-lasting analgesic for post-surgical pain.

BLIS is an extended-release formulation of bupivacaine, and a single injection of BLIS can provide up to 72 hours of analgesia.

Analyzing the use of carprofen for dogs with osteoarthritis and the additional benefits that can be seen with the use of adjunctive agents.

Carprofen for dogs with osteoarthritis has been shown to reduce pain, and additional benefits can be seen with the use of adjunctive agents.

Maropitant can be an effective antiemetic in felines and is also useful as an adjunct to therapy for visceral pain.

Maropitant can be an effective antiemetic in felines and is also useful as an adjunct to therapy for visceral pain.

Sarolaner is highly effective against fleas and ticks on dogs when dosed once monthly.

Sarolaner is an ectoparasiticide that is effective against fleas and ticks on dogs when administered once a month. This article covers its development, mechanism of action, dosage, safety, and efficacy against 6 common species of ectoparasites. It also compares the safety and efficacy of sarolaner with those of 2 other popular ectoparasiticides in the same class: afoxolaner and fluralaner.

Oral cyclosporine is currently being used to treat a spectrum of inflammatory and immune-mediated diseases in dogs.

Cyclosporine is a potent immunosuppressive agent that has treatment applications in both veterinary and human medicine. Oral cyclosporine is currently being used to treat a spectrum of inflammatory and immune-mediated diseases in dogs, including but not limited to atopic dermatitis, autoimmune skin disorders, perianal fistula, inflammatory bowel disease, granulomatous meningoencephalitis, and immune-mediated blood disorders.